Detailed Notes on megatomi.com

Our new Clear+ tissue clearing method is the only process that delipidates samples without adjust in morphology and with minimum influence on structural integrity.

Megatome is usually a vibrating microtome designed to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With substantial blade vibrating frequency and minimized blade deflection, Megatome permits significant-throughput tissue sectioning with uniform area profile, as well as minimal tissue harm and data reduction.

Antibodies might get weeks to diffuse via only a few millimeters of tissue, using a steep labeling gradient from surface area to core.

Megatome is made for accuracy: the blade vibrates at a higher frequency and larger amplitude range than other microtomes, and features a unique deflection control system.

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Our preformulated EasyIndex Alternative raises and homogenize the refractive index of delipidated tissue samples, rendering them thoroughly transparent. This enables light-weight penetration in the sample and assures the acquisition of higher-resolution, in-focus graphic knowledge.

Megatome is actually a novel microtome that allows for prime-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human Mind hemispheres – with nominal tissue damage and data loss.

eFLASH is usually a speedy tissue labeling technique that enables for uniform whole-organ staining in twenty rounds of labeling.

Absolutely delipidate complete mouse brains or comparably sized samples in only one day with SmartBatch+, megatomi.com or in a single week with our passive clearing package.

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Leverage the Obvious+ tissue clearing process, along with eFLASH and patented stochastic electrotransport technologies, to promptly distinct and label complete organs. Essential highlights and options include:

Our novel SHIELD tissue preservation approach varieties intramolecular bonds working with polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.